منابع مشابه
IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase.
Toll/IL-1 receptor family members are central components of host defense mechanisms in a variety of species. One well conserved element in their signal transduction is Ser/Thr kinases, which couple early signaling events in a receptor complex at the plasma membrane to larger signalosomes in the cytosol. The fruit fly Drosophila melanogaster has one member of this family of kinases, termed Pelle...
متن کاملIRAK-4 Inhibitors for Inflammation
Interleukin-1 receptor-associated kinases (IRAKs) are key components in the signal transduction pathways utilized by interleukin-1 receptor (IL-1R), interleukin-18 receptor (IL-18R), and Toll-like receptors (TLRs). Out of four members in the mammalian IRAK family, IRAK-4 is considered to be the "master IRAK", the only family member indispensable for IL-1R/TLR signaling. In humans, mutations res...
متن کاملHochwasser in der Wüste? Hochwassermodellierung am Beispiel der Großstadt Hafar Al Batin in Saudi Arabien
Hafar Al Batin liegt in der Ostprovinz Saudi-Arabiens, ca. 70 km südlich der Grenze nach Kuwait und Irak und ca. 200 km im Landesinneren. Die Stadt hat rund 400.000 Einwohner und erstreckt sich im und entlang des Wadi al Batin. Dieses Wadi ist das größte der arabischen Halbinsel und entwässert ein Gebiet von rund 60.000 km, was der 1,5 fachen Fläche der Schweiz entspricht. Zudem münden in Hafar...
متن کاملIRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family.
The interleukin-1 receptor-associated kinase (IRAK) was first described as a signal transducer for interleukin-1 (IL-1) and has later been implicated in signal transduction of other members of the Toll/IL-1 receptor family. We now report the identification and characterization of a novel IRAK-like molecule. In contrast to the ubiquitously expressed IRAK and IRAK-2, this new IRAK-like molecule i...
متن کاملExperimental and numerical infiltration studies in a wadi stream bed
Moisture content data from an infiltration experiment undertaken in the dry main stream bed of wadi Habawnah, south-west Saudi Arabia, are reported. A simple experiment enabled hydraulic properties of the multi-layer soil profile to be inferred through inversion of an unsaturated soil water simulation model. The results indicate a heterogeneous but highly transmissive profile and suggest that s...
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ژورنال
عنوان ژورنال: Informes de la Construcción
سال: 1959
ISSN: 1988-3234,0020-0883
DOI: 10.3989/ic.1959.v12.i108.5432